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DeCS
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Descriptor English:
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Molindone
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Descriptor Spanish:
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Molindona
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Descriptor Portuguese:
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Molindona
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Synonyms English:
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Moban
Molindone Hydrochloride
Molindone Monohydrochloride
Hydrochloride, Molindone
Monohydrochloride, Molindone
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Tree Number:
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D03.633.100.473.629
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Definition English:
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An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual, 1994, p283) |
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Pharmacological Action:
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Antipsychotic Agents
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History Note English:
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91(72); was see under INDOLES 1972-90
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Allowable Qualifiers English:
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Record Number:
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9160
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Unique Identifier:
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D008972
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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